Bryan Cox Selected Research

2- (3,4- difluorophenyl)- 4- (3- hydroxy- 3- methylbutoxy)- 5- (4- methanesulfonylphenyl)- 2H- pyridazin- 3- one

12/2004

ABT-963 [2-(3,4-difluoro-phenyl)-4-(3-hydroxy-3-methyl-butoxy)-5-(4-methanesulfonyl-phenyl)-2H-pyridazin-3-one], a highly potent and selective disubstituted pyridazinone cyclooxgenase-2 inhibitor.

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Bryan Cox Research Topics

Disease

2	Neoplasms (Cancer) 04/2022 - 01/2014
1	Pancreatic Neoplasms (Pancreatic Cancer) 04/2022
1	Adenocarcinoma 04/2022
1	Peripheral Nervous System Diseases (PNS Diseases) 04/2022
1	Infections 01/2021
1	Virus Diseases (Viral Diseases) 01/2021
1	Chronic Hepatitis B 01/2021
1	Non-alcoholic Fatty Liver Disease 01/2020
1	Body Weight (Weight, Body) 01/2020
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020
1	Weight Gain 01/2020
1	Human Influenza (Influenza) 10/2019
1	Zika Virus Infection 01/2017
1	Congenital Abnormalities (Deformity) 01/2017
1	Hepatocellular Carcinoma (Hepatoma) 01/2014
1	Uremia 01/2010
1	Chronic Renal Insufficiency 01/2010
1	Arthritis (Polyarthritis) 12/2004
1	Edema (Dropsy) 12/2004
1	Hyperalgesia 12/2004
1	Inflammation (Inflammations) 12/2004
1	Pain (Aches) 12/2004
1	Experimental Arthritis 12/2004

Drug/Important Bio-Agent (IBA)

2	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2017
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 04/2022
1	antagomir-122IBA 01/2020
1	Triglycerides (Triacylglycerol)IBA 01/2020
1	MicroRNAs (MicroRNA)IBA 01/2020
1	Member 1 Group F Nuclear Receptor Subfamily 1IBA 01/2020
1	thienopyrimidineIBA 10/2019
1	pimodivirIBA 10/2019
1	VaccinesIBA 01/2017
1	Chloroquine (Aralen)FDA LinkGeneric 01/2014
1	Therapeutic UsesIBA 01/2014
1	EF25-(GSH)2IBA 01/2014
1	CurcuminIBA 01/2014
1	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2010
1	salicylhydroxamic acid (SHAM)IBA 01/2010
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2010
1	paricalcitol (Zemplar)FDA Link 01/2010
1	CarrageenanIBA 12/2004
1	2- (3,4- difluorophenyl)- 4- (3- hydroxy- 3- methylbutoxy)- 5- (4- methanesulfonylphenyl)- 2H- pyridazin- 3- oneIBA 12/2004
1	valdecoxib (Bextra)FDA Link 12/2004
1	rofecoxib (Vioxx)FDA Link 12/2004
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 12/2004
1	Dinoprostone (PGE2)FDA Link 12/2004
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 12/2004
1	Celecoxib (Celebrex)FDA Link 12/2004
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 12/2004

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 04/2022
1	Injections 01/2020
1	Therapeutics 01/2017
1	Oral Administration 12/2004